USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9UQF9 USC-OGP 2-DE database:  Q9UQF9 Q9UQF9 General information about the entry View entry in simple text format Entry name LYPA1_HUMAN Primary accession number Q9UQF9 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I;. Gene name Name=LYPLA1 Synonyms=APT1, LPL1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0545: pI=6.10; Mw=23617 Cross-references UniProtKB/Swiss-Prot O75608; LYPA1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LYPA1_HUMAN Primary accession number O75608 Secondary accession number(s) O43202 Q9UQF9 Sequence was last modified on  November 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 156) Name and origin of the protein Description RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I; Gene name Name=LYPLA1 Synonyms=APT1, LPL1 Encoded on Name=LYPLA1; Synonyms=APT1, LPL1 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Fatty acid metabolism; Hydrolase; Lipid metabolism; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF081281; AAC31610.1; -; mRNA EMBL AF291053; AAG10063.1; -; mRNA EMBL AF077198; AAD26993.1; -; mRNA EMBL AF077199; AAD26994.1; -; mRNA EMBL BC008652; AAH08652.1; -; mRNA EMBL BC010397; AAH10397.1; -; mRNA EMBL AF035293; AAB88180.1; ALT_INIT; mRNA CCDS CCDS6157.1; -. [O75608-1]; . CCDS CCDS64899.1; -. [O75608-2]; . RefSeq NP_001266285.1; NM_001279356.1; . RefSeq NP_001266286.1; NM_001279357.1. [O75608-2]; . RefSeq NP_001266287.1; NM_001279358.1; . RefSeq NP_001266288.1; NM_001279359.1; . RefSeq NP_001266289.1; NM_001279360.1; . RefSeq NP_006321.1; NM_006330.3. [O75608-1]; . UniGene Hs.744046; -; . PDB 1FJ2; X-ray; 1.50 A; A/B=6-230 PDB 5SYM; X-ray; 1.55 A; A/B=1-230 PDBsum 1FJ2; -; . PDBsum 5SYM; -; . ProteinModelPortal O75608; -; . SMR O75608; -; . BioGrid 115701; 22; . IntAct O75608; 4; . MINT MINT-5005801; -; . STRING 9606.ENSP00000320043; -; . BindingDB O75608; -; . ChEMBL CHEMBL1681631; -; . SwissLipids SLP:000000734; -; . ESTHER human-LYPLA1; LYsophospholipase_carboxylesterase; . MEROPS S09.941; -; . iPTMnet O75608; -; . PhosphoSitePlus O75608; -; . SwissPalm O75608; -; . BioMuta LYPLA1; -; . OGP O75608; -; . EPD O75608; -; . PaxDb O75608; -; . PeptideAtlas O75608; -; . PRIDE O75608; -; . DNASU 10434; -; . Ensembl ENST00000316963; ENSP00000320043; ENSG00000120992. [O75608-1]; . Ensembl ENST00000343231; ENSP00000344477; ENSG00000120992. [O75608-2]; . GeneID 10434; -; . KEGG hsa:10434; -; . UCSC uc003xrz.5; human. [O75608-1]; . CTD 10434; -; . DisGeNET 10434; -; . GeneCards LYPLA1; -; . HGNC HGNC:6737; LYPLA1; . HPA HPA050941; -; . HPA HPA063151; -; . MIM 605599; gene; . neXtProt NX_O75608; -; . OpenTargets ENSG00000120992; -; . PharmGKB PA30499; -; . eggNOG KOG2112; Eukaryota; . eggNOG COG0400; LUCA; . GeneTree ENSGT00390000009648; -; . HOGENOM HOG000260139; -; . HOVERGEN HBG052378; -; . InParanoid O75608; -; . KO K06128; -; . OMA VEWHEYS; -; . OrthoDB EOG091G080L; -; . PhylomeDB O75608; -; . TreeFam TF314619; -; . BRENDA 3.1.2.22; 2681; . Reactome R-HSA-203615; eNOS activation; . ChiTaRS LYPLA1; human; . EvolutionaryTrace O75608; -; . GeneWiki LYPLA1; -; . GenomeRNAi 10434; -; . PRO PR:O75608; -; . Proteomes UP000005640; Chromosome 8; . Bgee ENSG00000120992; -; . CleanEx HS_LYPLA1; -; . ExpressionAtlas O75608; baseline and differential; . Genevisible O75608; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0016298; F:lipase activity; IDA:CACAO; . GO GO:0004622; F:lysophospholipase activity; TAS:ProtInc; . GO GO:0008474; F:palmitoyl-(protein) hydrolase activity; IMP:UniProtKB; . GO GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW; . GO GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; IEA:Ensembl; . GO GO:0002084; P:protein depalmitoylation; IBA:GO_Central; . GO GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome; . Gene3D 3.40.50.1820; -; 1; . InterPro IPR029058; AB_hydrolase; . InterPro IPR003140; PLipase/COase/thioEstase; . Pfam PF02230; Abhydrolase_2; 1; . SUPFAM SSF53474; SSF53474; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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